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Influenza vaccination of elderly persons. Reduction in pneumonia and influenza hospitalizations and deaths.

Identifieur interne : 000191 ( 1968/Analysis ); précédent : 000190; suivant : 000192

Influenza vaccination of elderly persons. Reduction in pneumonia and influenza hospitalizations and deaths.

Auteurs : W H Barker ; J P Mullooly

Source :

RBID : pubmed:7431593

Descripteurs français

English descriptors

Abstract

Effectiveness of influenza vaccination in reducing pneumonia and influenza hospitalizations and deaths among elderly members of a prepaid health plan was analyzed retrospectively. Two epidemics caused by the H3N2 subtype of type A influenza were studied. Vaccine derived from the H2N2 subtype of influenza A virus failed to protect against the Hong Kong (H3N2) virus during the 1968-1969 epidemic. Vaccine derived from the A/Hong Kong/68 (H3N2) virus yielded an estimated 72% (31% to 100%) reduction in hospitalization and 87% (52% to 100%) reduction in mortality during the 1972-1973 epidemic caused by A/England/72 (H3N2). These findings are consistent with those reported in vaccinated young persons, and hence it appears they may be broadly generalized.

PubMed: 7431593


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pubmed:7431593

Le document en format XML

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<term>Health Services Research</term>
<term>Hospitalization (trends)</term>
<term>Humans</term>
<term>Influenza Vaccines (administration & dosage)</term>
<term>Influenza, Human (mortality)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Mortality</term>
<term>Oregon</term>
<term>Pneumonia (prevention & control)</term>
<term>Pneumonia, Viral (prevention & control)</term>
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<term>Retrospective Studies</term>
<term>Vaccination (statistics & numerical data)</term>
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<term>Facteurs de l'âge</term>
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<term>Hospitalisation (tendances)</term>
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<term>Influenza Vaccines</term>
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<term>Influenza, Human</term>
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<term>Grippe humaine</term>
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<term>Influenza, Human</term>
<term>Pneumonia</term>
<term>Pneumonia, Viral</term>
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<term>Vaccination</term>
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<term>Pneumopathie virale</term>
<term>Probabilité</term>
<term>Recherche sur les services de santé</term>
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<div type="abstract" xml:lang="en">Effectiveness of influenza vaccination in reducing pneumonia and influenza hospitalizations and deaths among elderly members of a prepaid health plan was analyzed retrospectively. Two epidemics caused by the H3N2 subtype of type A influenza were studied. Vaccine derived from the H2N2 subtype of influenza A virus failed to protect against the Hong Kong (H3N2) virus during the 1968-1969 epidemic. Vaccine derived from the A/Hong Kong/68 (H3N2) virus yielded an estimated 72% (31% to 100%) reduction in hospitalization and 87% (52% to 100%) reduction in mortality during the 1972-1973 epidemic caused by A/England/72 (H3N2). These findings are consistent with those reported in vaccinated young persons, and hence it appears they may be broadly generalized.</div>
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